
Alec Baldwin - played Holmes on stage of Stephen Lawson's adaption of, A Study in Scarlet 1987
Michael Caine - played Holmes as a drunken actor in the excellent Without a Clue. Though to be precise he was playing an actor hired to be Sherlock Holmes but that's splitting hairs.
John Cleese - The Python giant was Holmes twice,once in 1973 and then again in 1977
Peter Cook - was Holmes in the dreadful comedy spoof, The Hound
Francis Ford - brother of director John Ford played the part in a 1914 version of A Study in Scarlet for Gold Seal( Universal) Films.

Stewert Granger - in Universal's 1972 TV movie of The HOund of the Baskervilles
Larry Hagman - JR himself in a 1976 Universal TVpilot, The World's Greatest Detecive. A proposed series never came about.
Charlton Heston - on stage in the Crucifer of Blood in 1980. Jeremy Brett, perhaps the screens's greatest Holmes was Watson to old Chuck's Holmes.
Roger Moore - In the dire Sherlock Holmes in New York, 20th Century Fox1976

Leonard Nimoy -on stage in a 1974 US tour. Also in the educational TV programme, The Interior Motive which had Holmes explaining the formation of the Earth.
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